bpV (HOpic)

CAS No. 722494-26-0

bpV (HOpic)( —— )

Catalog No. M21158 CAS No. 722494-26-0

bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).?

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 77 Get Quote
5MG 129 Get Quote
10MG 203 Get Quote
25MG 412 Get Quote
50MG 590 Get Quote
100MG 827 Get Quote
200MG Get Quote Get Quote
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Biological Information

  • Product Name
    bpV (HOpic)
  • Note
    Research use only, not for human use.
  • Brief Description
    bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).?
  • Description
    bpV (HOpic) is a potent inhibitor of PTEN (IC50 of 14 nM).?
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Wistar rats are subjected to partial hepatic ischemia Dosage:0.05 mg/kg Administration:I.p. injections at the start of reperfusionResult:Ameliorated reoxygenation injury and reproduced the hepatoprotective effects obtained by adenosine A2A receptor stimulation.Animal Model:Male C57BL/6 mice (8-12 weeks old; 20-30 g ) are subjected to renal ischemia Dosage:200?μg/kg Administration:I.p. injections 1?h before ischemia and then administers every 6?h after ischemia for 24 hr Result:Raised the level of serum creatinine and blood serum urea nitrogen.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    PTEN
  • Recptor
    PTEN
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    722494-26-0
  • Formula Weight
    347.24
  • Molecular Formula
    C6H4K2NO8V
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:69 mg/mL (198.71 mM)
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Dimchev GA Al-Shanti N Stewart CE.Phospho-tyrosine phosphatase inhibitor Bpv(Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways.J Muscle Res Cell Motil. 2013 May;34(2):125-36.
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